Description

Propionic-2,2-D2 Acid is a deuterium-labeled isotopologue of propionic acid, where two hydrogen atoms at the 2-position are replaced with deuterium (CAS NO 19136-91-5). This isotopic labeling makes it an essential tool in advanced research, providing a stable, non-radioactive tracer for mechanistic studies and analytical method development. It is primarily needed by the pharmaceutical, agrochemical, and academic research sectors for applications in metabolic pathway tracing, NMR spectroscopy, and mass spectrometry.

Application

• As an internal standard or reference material in quantitative mass spectrometry (MS) and nuclear magnetic resonance (NMR) spectroscopy.
• For mechanistic studies and metabolic pathway tracing in pharmaceutical and biochemical research.
• In the synthesis of deuterium-labeled fine chemicals, pharmaceutical intermediates, and active pharmaceutical ingredients (APIs).
• As a tracer in environmental fate studies and agrochemical research.
• For use in analytical method development and validation to ensure accuracy and regulatory compliance.
• In material science research, particularly in studies involving reaction kinetics and isotope effects.

Basic Information

Product Name	Propionic-2,2-D2 Acid
CAS No.	19136-91-5
Molecular Formula	C3D2H4O2
Molecular Weight	76.09 g/mol
Synonyms	Deuterated Propionic Acid; 2,2-Dideuteropropanoic Acid; Propanoic-2,2-d2 Acid; [2,2-2H2]Propionic Acid; Propionic Acid-d2; CD3CH2COOD (common notation); (2,2-2H)Propionic Acid
EINECS	Contact for details

Quality Control

Our deuterated chemicals, including Propionic-2,2-D2 Acid, undergo rigorous quality testing to ensure high isotopic purity and chemical purity suitable for sensitive analytical applications. We provide comprehensive analytical data, including results from NMR, MS, and HPLC. Certificates of Analysis (COA) detailing isotopic enrichment (atom % D), chemical purity, and impurity profiles are available upon request to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound is a strong acid/organic solvent; keep away from incompatible materials such as strong bases, oxidizing agents, and amines. Ensure containers are kept upright to prevent leakage.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Atom % D)	≥ 98.0% (by 1H NMR or MS)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.