Description

Tetrahydro-2H-Thiopyran-3-One is a versatile sulfur-containing heterocyclic compound, specifically a thiopyranone, that serves as a valuable building block in advanced organic synthesis. Its unique structure makes it a critical intermediate for developing novel pharmaceuticals, agrochemicals, and functional materials. This high-purity chemical is essential for research and development chemists and process engineers in the fine chemical, pharmaceutical, and life science industries seeking to introduce sulfur-based functionalities into complex molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting neurological and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, where the thiopyranone core contributes to biological activity.
• Ligand and Catalyst Precursor: Serves as a starting material for synthesizing specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the development of organic electronic materials, polymers, and liquid crystals due to its electron-rich sulfur heterocycle.
• Flavor and Fragrance Chemistry: Acts as a potential intermediate for creating sulfur-containing aroma compounds with unique sensory profiles.
• Academic and R&D Laboratories: A valuable reagent for methodological studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	Tetrahydro-2H-Thiopyran-3-One
CAS No.	19090-03-0
Molecular Formula	C5H8OS
Molecular Weight	116.18 g/mol
Synonyms	3-Oxotetrahydro-2H-thiopyran; Tetrahydro-2H-thiopyran-3-one; 3-Thiacyclohexanone; 3-Oxo-tetrahydro-thiopyran; 3-Ketotetrahydrothiopyran; Thiacyclohexan-3-one; 3-Oxoperhydrothiopyran
EINECS	Contact for details

Quality Control

Our Tetrahydro-2H-Thiopyran-3-One is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our commitment to quality supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.