Description

4-Bromobutyric Acid, [1-14C] is a carbon-14 labeled derivative of 4-bromobutyric acid, a key building block in organic synthesis. This radiolabeled compound is essential for conducting precise metabolic and pharmacokinetic studies, enabling researchers to track the fate of molecules within complex biological systems. It is primarily utilized by pharmaceutical R&D teams, agrochemical scientists, and academic researchers in the fields of medicinal chemistry and tracer technology for drug development and biochemical pathway analysis.

Application

• Tracer Studies in Drug Metabolism and Pharmacokinetics (DMPK): Used as a radiolabeled precursor to synthesize candidate drugs for tracking absorption, distribution, metabolism, and excretion (ADME) profiles.
• Medicinal Chemistry Research: Serves as a key intermediate for the synthesis of complex molecules where the carbon-14 label is incorporated for mechanistic and degradation studies.
• Biochemical Pathway Analysis: Employed to elucidate metabolic pathways and identify potential metabolites in both mammalian and environmental systems.
• Agrochemical Research: Used in the development and environmental fate studies of new pesticides and herbicides.
• Reference Standard: Acts as an analytical standard for quantification and method validation in radiochemical analysis.

Basic Information

Product Name	4-Bromobutyric Acid, [1-14C]
CAS No.	19067-38-0
Molecular Formula	C4H714CO2Br
Molecular Weight	~167.00 g/mol (for unlabeled); Specific activity provided on COA.
Synonyms	4-Bromo[1-14C]butyric Acid; γ-Bromo[1-14C]butyric Acid; [1-14C]-4-Bromobutanoic Acid; NSC 60512 (labeled); Butyric-1-14C acid, 4-bromo-; ω-Bromo[1-14C]butyric Acid; 4-Bromobutanoic-1-14C Acid
EINECS	Contact for details

Quality Control

Every batch of 4-Bromobutyric Acid, [1-14C] is manufactured and analyzed under strict quality control protocols to ensure high chemical and radiochemical purity. Our products undergo rigorous testing, including HPLC and radio-HPLC analysis, to confirm identity, specific activity, and radiochemical purity. A comprehensive Certificate of Analysis (COA) detailing all specifications, including purity, specific activity, and solvent content, is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at recommended temperatures (typically 2-8°C or as specified on the label) in a dedicated, well-ventilated area for radioactive materials. Keep away from strong acids and organic solvents. Follow all local and international regulations for the storage and handling of radioactive substances.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR / NMR)	Conforms to structure
Assay (HPLC)	≥ 98% (Chemical Purity)
Radiochemical Purity (Radio-HPLC)	≥ 97%
Specific Activity	Customizable (mCi/mmol)
Solvent	Specified on COA (e.g., Ethanol, Toluene)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.