Description

Heptanedioic-2,2,6,6-D4 Acid is a deuterium-labeled analog of pimelic acid, a seven-carbon dicarboxylic acid. This stable isotope-labeled compound is essential for advanced analytical research, providing a non-radioactive tracer with distinct mass spectral properties. It is primarily used by researchers and scientists in pharmaceutical development, metabolic studies, and analytical chemistry who require precise internal standards for mass spectrometry.

Application

• Internal Standard for Mass Spectrometry (MS): Serves as a critical quantitative internal standard in LC-MS and GC-MS analysis for accurate measurement of pimelic acid and related metabolites.
• Metabolic Pathway Tracing: Used in biomedical and biochemical research to study fatty acid biosynthesis, lysine metabolism, and other metabolic pathways utilizing deuterium as a stable tracer.
• Pharmaceutical Impurity Profiling & PK/PD Studies: Enables precise tracking of drug metabolites and impurities in pharmacokinetic/pharmacodynamic research during drug development.
• NMR Spectroscopy: Acts as a useful probe in Nuclear Magnetic Resonance (NMR) studies due to the distinct signal of deuterium atoms.
• Chemical Synthesis Intermediate: Used in the synthesis of more complex deuterium-labeled compounds for research purposes.
• Quality Control & Method Development: Employed in analytical laboratories for developing and validating robust analytical methods for dicarboxylic acid analysis.

Basic Information

Product Name	Heptanedioic-2,2,6,6-D4 Acid
CAS No.	19031-56-2
Molecular Formula	C7H6D4O4
Molecular Weight	164.18 g/mol (for C7H6D4O4)
Synonyms	Pimelic-2,2,6,6-d4 Acid; Pimelic Acid-d4; 1,5-Pentanedicarboxylic-2,2,6,6-d4 Acid; Heptanedioic-d4 Acid; Deuterated Pimelic Acid; [2,2,6,6-2H4]Heptanedioic Acid; 1,7-Heptanedioic-2,2,6,6-d4 Acid
EINECS	Contact for details

Quality Control

Our Heptanedioic-2,2,6,6-D4 Acid is produced under strict quality protocols to ensure high isotopic purity and chemical integrity, suitable for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as isotopic enrichment (atom % D), chemical purity (by HPLC or NMR), and identification. We adhere to relevant industry standards for stable isotope-labeled compounds.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Isotopic Purity (Atom % D)	≥ 98% (by 1H NMR or MS)
Chemical Purity (HPLC)	≥ 98%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.