Description

D-Glucose-6,6-D2 is a stable isotope-labeled analog of D-glucose, specifically deuterated at the 6,6 positions. This precise labeling makes it an invaluable internal standard and tracer for metabolic research and quantitative analytical techniques. It is essential for scientists and researchers in pharmaceutical development, clinical diagnostics, and biochemistry who require high-purity, isotopically defined compounds. The product is supplied under stringent quality control to ensure batch-to-batch consistency for reliable experimental results.

Application

• Mass Spectrometry Internal Standard: Used as a quantitative reference standard in LC-MS and GC-MS analysis of glucose and related metabolites in biological samples.
• Metabolic Pathway Tracing: Employed in in vitro and in vivo studies to elucidate glucose uptake, glycolysis, and other metabolic fluxes using NMR or MS detection.
• Pharmaceutical Research: Serves as a critical tool in drug metabolism and pharmacokinetics (DMPK) studies for tracking the fate of glucose-based compounds.
• Clinical Diagnostics Development: Utilized in the development and calibration of advanced assays for diabetes research and metabolic disorder diagnostics.
• Biochemical Research: Acts as a substrate or tracer in enzymatic studies and investigations of carbohydrate metabolism.
• Stable Isotope Labeling: Used in the synthesis of more complex deuterated molecules for research purposes.

Basic Information

Product Name	D-Glucose-6,6-D2
CAS No.	18991-62-3
Molecular Formula	C6H10D2O6
Molecular Weight	182.17 g/mol
Synonyms	6,6-Dideutero-D-glucose; Deuterated D-Glucose; D-Glucose-6,6-d2; (2R,3S,4R,5R)-2,3,4,5,6-Pentahydroxyhexanal-6,6-d2; D-(+)-Glucose-6,6-D2; 6,6-Dideutero-D-glucopyranose; D-Glucose (6,6-D2)
EINECS	Contact for details

Quality Control

Our D-Glucose-6,6-D2 is manufactured and handled under a strict quality management system. Each batch undergoes comprehensive analytical testing, including NMR and mass spectrometry, to confirm isotopic enrichment, chemical purity, and identity. A Certificate of Analysis (COA) detailing the specific results for purity, isotopic abundance, and other critical parameters is provided with every shipment to ensure full traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent absorption of moisture. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Specific Optical Rotation	+52.5° to +53.5° (c=10 in H2O)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.