Description

5-Iodo-2-Thiophenecarbonitrile is a versatile halogenated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. Industries requiring high-purity chemical intermediates for research, process development, and commercial manufacturing will find this product essential for constructing novel thiophene-based architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for molecules targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the thiophene scaffold for bioactivity.
• Material Science & Organic Electronics: Serves as a building block for conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs), organic photovoltaics (OPVs), and field-effect transistors (OFETs).
• Ligand & Catalyst Synthesis: Employed in the preparation of specialized ligands for transition metal catalysis, facilitating cross-coupling and other key synthetic transformations.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D exploring new synthetic methodologies and heterocyclic chemistry.
• Dye & Pigment Intermediate: Used in the synthesis of specialized dyes and functional colorants.

Basic Information

Item	Detail
Product Name	5-Iodo-2-Thiophenecarbonitrile
CAS No.	18945-81-8
Molecular Formula	C5H2INS
Molecular Weight	234.04 g/mol
Synonyms	5-Iodothiophene-2-carbonitrile; 2-Cyano-5-iodothiophene; 5-Iodo-2-cyanothiophene; 5-Iodothieno[2,3-c]pyridine? (Common mis-assignment, verify structure); Thiophene-2-carbonitrile, 5-iodo-; 18945-81-8; 5-Iodo-thiophene-2-carbonitrile
EINECS	Contact for details

Quality Control

Our 5-Iodo-2-Thiophenecarbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.