Description

Deuteroheme is a stable, isotopically labeled porphyrin complex where the iron center is coordinated within a deuterated protoporphyrin IX framework. This compound is critical for advanced spectroscopic and analytical research, providing a non-interfering internal standard for mass spectrometry and a probe for studying heme protein dynamics without spectral overlap. It is primarily utilized by research institutions, pharmaceutical developers, and diagnostic manufacturers engaged in metabolic pathway analysis, biomarker discovery, and the development of novel therapeutic agents.

Application

• Internal Standard for Mass Spectrometry: Used in quantitative LC-MS/MS analysis of heme and related metabolites in biological samples.
• Biochemical Research Probe: Employed in NMR and resonance Raman spectroscopy to investigate the structure and function of hemoproteins like cytochromes and peroxidases.
• Isotopic Tracer Studies: Facilitates the tracing of heme biosynthesis and degradation pathways in metabolic research.
• Pharmaceutical Development: Serves as a reference material in the development and quality control of heme-based pharmaceuticals and diagnostics.
• Analytical Method Development: Essential for validating analytical methods in clinical and forensic toxicology labs.

Basic Information

Product Name	Deuteroheme
CAS No.	18922-88-8
Molecular Formula	C34H28D4N4O4Fe
Molecular Weight	616.51 g/mol
Synonyms	Iron Deuteroporphyrin IX; Deuterohaem; Deuterohemin; Deuteroporphyrin IX Iron(III) Chloride; (Deutero)hemin; Deuterated Hemin; Deuteroferroheme; 7,12-Diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(2-)-κN21,κN22,κN23,κN24]iron; Deuterohaemin
EINECS	242-690-0

Quality Control

Our Deuteroheme is manufactured under controlled conditions to ensure high isotopic enrichment and chemical purity. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as isotopic purity, assay, and impurity profile. We adhere to rigorous quality testing protocols suitable for research and development applications. Certificates of Analysis are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Dark brown to black crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Isotopic Purity (D-content)	≥ 98 atom % D
Assay (Titration)	≥ 90% (on dried basis)
Loss on Drying	≤ 2.0 %
Residue on Ignition	≤ 0.5 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.