Description

2-Methylthiazole-4,5-Dicarboxylic Acid Diethyl Ester is a high-purity, versatile heterocyclic building block essential for advanced organic synthesis. This compound is valued for its role as a key precursor in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought by research chemists and process development scientists for constructing thiazole-based scaffolds, which are core structures in numerous active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor for synthesizing novel drug candidates, especially those targeting infectious diseases or metabolic disorders.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with thiazole moieties.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in coordination chemistry and catalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials and advanced polymers.
• Chemical Biology Probes: Useful for building fluorescent tags or molecular probes for biochemical research.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke fine chemicals and advanced intermediates.

Basic Information

Product Name	2-Methylthiazole-4,5-Dicarboxylic Acid Diethyl Ester
CAS No.	18903-17-8
Molecular Formula	C11H15NO4S
Molecular Weight	257.31 g/mol
Synonyms	Diethyl 2-Methyl-4,5-thiazoledicarboxylate; 2-Methyl-4,5-thiazoledicarboxylic Acid Diethyl Ester; 4,5-Thiazoledicarboxylic Acid, 2-Methyl-, Diethyl Ester; Ethyl 2-Methylthiazole-4,5-dicarboxylate; 18903-17-8; NSC 163044; AI3-28400; Diethyl 2-methyl-1,3-thiazole-4,5-dicarboxylate
EINECS	Contact for details

Quality Control

Our production of 2-Methylthiazole-4,5-Dicarboxylic Acid Diethyl Ester adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with each shipment, detailing all relevant specifications. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.