Description

2-Iodo-3-Thiophenecarboxylicacid is a halogenated heterocyclic building block of significant importance in advanced organic synthesis. Its unique structure, featuring both an iodine substituent and a carboxylic acid functional group on a thiophene ring, makes it a versatile intermediate for constructing complex molecules. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and anti-infectives.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiophene scaffold.
• Material Science: Serves as a monomer or functionalizing agent in the production of conductive polymers, organic semiconductors, and liquid crystals.
• Organic Ligand Preparation: The carboxylic acid group allows for the creation of custom ligands for catalysis and metal-organic frameworks (MOFs).
• Cross-Coupling Reactions: The iodine atom is an excellent handle for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to form carbon-carbon bonds.
• Chemical Research: Employed in academic and industrial R&D for exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	2-Iodo-3-Thiophenecarboxylicacid
CAS No.	18895-00-6
Molecular Formula	C5H3IO2S
Molecular Weight	253.05 g/mol
Synonyms	3-Thiophenecarboxylic acid, 2-iodo-; 2-Iodothiophene-3-carboxylic acid; 2-Iodo-3-thiophenecarboxylic acid; 2-Iodothiophene-3-carboxylicacid; 3-Carboxy-2-iodothiophene; 2-Iodo-3-carboxythiophene; 18895-00-6; Thiophene-3-carboxylic acid, 2-iodo-
EINECS	Contact for details

Quality Control

Our 2-Iodo-3-Thiophenecarboxylicacid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing specifications such as assay (by HPLC), related substances, and residual solvents is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.