Description

[R,(-)]-1-o-[(2-Aminoethyl)Phosphonyl]-D-Glycerol is a specialized chiral phosphonic acid derivative of glycerol, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both amino and phosphonyl functional groups on a glycerol backbone, makes it a valuable precursor for creating complex molecules with specific stereochemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients, prodrugs, and enzyme inhibitors where precise molecular geometry is paramount.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of novel therapeutic agents, including antiviral and anticancer drugs.
• Biochemical Research: Used as a substrate analog or inhibitor in enzymatic studies, particularly those involving kinases, phosphatases, and phospholipases.
• Prodrug Development: Serves as a versatile linker or carrier moiety in the design of prodrugs to improve drug solubility, stability, or targeted delivery.
• Agrochemical Synthesis: Intermediate in the production of advanced, stereospecific pesticides and herbicides.
• Ligand for Catalysis: Potential building block for chiral ligands used in asymmetric catalysis.
• Material Science: Monomer or modifier for synthesizing functional polymers and biomimetic materials.

Basic Information

Product Name	[R,(-)]-1-o-[(2-Aminoethyl)Phosphonyl]-D-Glycerol
CAS No.	18835-54-6
Molecular Formula	C5H14NO6P
Molecular Weight	215.14 g/mol
Synonyms	(R)-1-O-[(2-Aminoethyl)phosphonyl]-D-glycerol; (R)-1-O-(2-Aminoethylphosphono)-D-glycerol; D-Glycerol, 1-O-[(2-aminoethyl)phosphonyl]-, (R)-; 1-O-[(2-Aminoethyl)phosphonyl]-D-glycerol, (R)-(-)-form; (R)-(-)-1-O-(2-Aminoethylphosphono)glycerol; 2-Aminoethylphosphonic acid D-glycerol ester (R-isomer); AE-DG (R)
EINECS	Contact for details

Quality Control

Our [R,(-)]-1-o-[(2-Aminoethyl)Phosphonyl]-D-Glycerol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure high chemical and enantiomeric purity suitable for research and cGMP manufacturing. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccated conditions or under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.