Description

2-Iodo-3-Thiophenecarbaldehyde is a versatile halogenated heterocyclic building block, specifically an iodo-substituted thiophene aldehyde. This compound is valued for its dual reactive sites, making it a critical intermediate in advanced organic synthesis and materials science. It is primarily sought after by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules with thiophene-based scaffolds.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the thiophene ring contributes to biological activity.
• Organic Electronics: Serves as a building block for π-conjugated systems in the manufacture of organic semiconductors, OLEDs, and photovoltaic materials.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis and cross-coupling reactions (e.g., Suzuki, Sonogashira).
• Material Science Research: Utilized in academic and industrial R&D for creating novel polymers, dyes, and functional materials.
• Chemical Synthesis: Acts as a versatile electrophile for further functionalization via the aldehyde group and the iodine atom.

Basic Information

Product Name	2-Iodo-3-Thiophenecarbaldehyde
CAS No.	18812-40-3
Molecular Formula	C5H3IOS
Molecular Weight	237.95 g/mol
Synonyms	3-Formyl-2-iodothiophene; 2-Iodothiophene-3-carboxaldehyde; 2-Iodo-3-formylthiophene; 2-Iodothiophene-3-carbaldehyde; 3-Iodothiophene-2-carbaldehyde (isomer); Thiophene-3-carbaldehyde, 2-iodo-; 18812-40-3; 2-Iodo-3-thiophenecarboxaldehyde
EINECS	Contact for details

Quality Control

Our 2-Iodo-3-Thiophenecarbaldehyde is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high chemical purity and identity confirmation. We provide Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality systems are designed to support cGMP and ISO standards for reliable, batch-to-batch consistency in research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive and should be handled under appropriate conditions to prevent decomposition.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.