Description

2-Iodothiophene-3-Carbonitrile is a versatile halogenated heterocyclic building block of significant importance in advanced organic synthesis. Its unique structure, featuring both an iodine substituent and a nitrile group on a thiophene core, makes it a critical intermediate for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science: Serves as a monomer or building block for creating conductive polymers, organic semiconductors, and advanced electronic materials.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis, enabling more efficient cross-coupling reactions.
• Chemical Research: A valuable reagent for academic and industrial R&D in heterocyclic and medicinal chemistry for structure-activity relationship (SAR) studies.
• Dye and Pigment Intermediate: Used in the synthesis of specialized dyes and functional colorants.

Basic Information

Product Name	2-Iodothiophene-3-Carbonitrile
CAS No.	18800-01-6
Molecular Formula	C5H2INS
Molecular Weight	234.04 g/mol
Synonyms	3-Cyano-2-iodothiophene; 2-Iodo-3-thiophenecarbonitrile; 2-Iodothiophene-3-carbonitrile; Thiophene-3-carbonitrile, 2-iodo-; 3-Thiophenecarbonitrile, 2-iodo-; 2-Iodo-3-cyanothiophene; 2-Iodo-thiophene-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 2-Iodothiophene-3-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment ensures the material meets the stringent requirements for research and cGMP-grade pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should be performed under subdued light or amber glass containers when necessary for long-term stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.