Description

3-Pentynyl Bromide is a versatile alkyne-containing alkyl bromide building block, essential for advanced organic synthesis. Its terminal alkyne and reactive bromoalkyl functionalities make it a critical intermediate for constructing complex molecular architectures through cross-coupling and cycloaddition reactions. This compound is particularly valuable for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those requiring alkyne spacers or terminal alkyne handles for click chemistry.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and plant growth regulators that incorporate acetylene units.
• Material Science & Polymer Chemistry: Serves as a monomer or cross-linking agent in the development of specialty polymers, dendrimers, and conductive materials.
• Organic Synthesis & Chemical Research: A fundamental reagent for Sonogashira, Heck, and other palladium-catalyzed cross-coupling reactions to form carbon-carbon bonds.
• Ligand & Catalyst Development: Used to synthesize novel phosphine or nitrogen-based ligands with alkyne tethers for homogeneous catalysis.
• Bioconjugation & Probe Synthesis: Facilitates the labeling of biomolecules (proteins, nucleic acids) via copper-catalyzed azide-alkyne cycloaddition (CuAAC) for diagnostics and imaging.

Basic Information

Product Name	3-Pentynyl Bromide
CAS No.	18719-27-2
Molecular Formula	C5H7Br
Molecular Weight	147.01 g/mol
Synonyms	1-Bromo-3-pentyne; 3-Pentyne, 1-bromo-; 3-Pentyn-1-yl Bromide; 1-Bromo-3-pentyn; Bromopentyne; Pent-3-yn-1-yl Bromide; 5-Bromo-2-pentyne
EINECS	Contact for details

Quality Control

Every batch of our 3-Pentynyl Bromide is manufactured and tested under strict quality management systems to ensure consistency and reliability for your critical syntheses. We provide comprehensive analytical data, including purity by GC/HPLC, identity confirmation (IR, NMR), and impurity profiling. A Certificate of Analysis (COA) is supplied with each shipment, detailing all relevant specifications to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Due to its highly volatile nature, keep the container tightly sealed when not in use. Recommended storage temperature is 2-8°C for extended stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.