Description

3-Methoxy-1,2-Benzisothiazole 1,1-Dioxide is a versatile heterocyclic building block and key synthetic intermediate of significant interest in advanced organic chemistry. Its unique sulfonamide-containing benzisothiazole core makes it a valuable precursor for the development of novel pharmacologically active compounds and functional materials. This high-purity intermediate is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Research: Serves as a key precursor for developing new generations of herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science: Used in the research and development of advanced polymers, liquid crystals, and organic electronic materials due to its electron-deficient heterocyclic structure.
• Dye & Pigment Synthesis: Acts as an intermediate in the production of specialized dyes and functional pigments requiring a benzisothiazole backbone.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for constructing complex heterocyclic systems and as a scaffold for combinatorial chemistry libraries.

Basic Information

Product Name	3-Methoxy-1,2-Benzisothiazole 1,1-Dioxide
CAS No.	18712-14-6
Molecular Formula	C8H7NO3S
Molecular Weight	197.21 g/mol
Synonyms	3-Methoxybenzo[d]isothiazole 1,1-Dioxide; 3-Methoxy-1,2-benzisothiazole S,S-Dioxide; 1,2-Benzisothiazole, 3-methoxy-, 1,1-dioxide; 3-Methoxy-2,1-benzisothiazole 1,1-dioxide; Saccharin 3-Methyl Ether; 3-Methoxysaccharin
EINECS	Contact for details

Quality Control

Our 3-Methoxy-1,2-Benzisothiazole 1,1-Dioxide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.