Description

Thiophen-2-Amine Hydrochloride is a versatile organic salt widely utilized as a key synthetic intermediate in advanced chemical manufacturing. This compound is valued for its role in constructing complex heterocyclic structures, particularly in the development of active pharmaceutical ingredients and specialty agrochemicals. It is essential for research and production in the pharmaceutical, agrochemical, and material science industries, where high-purity building blocks are critical for process success and product efficacy.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of various drug candidates, particularly those containing thiophene rings, such as kinase inhibitors and antiviral agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides that require specific heterocyclic frameworks for enhanced activity.
• Material Science Research: Serves as a precursor for conducting polymers, organic semiconductors, and novel ligands for metal-organic frameworks (MOFs).
• Dye and Pigment Manufacturing: Employed in the synthesis of specialized colorants and pigments for industrial applications.
• Chemical Research & Development: A fundamental reagent in academic and industrial R&D labs for exploring new organic reactions and methodologies.
• Ligand Synthesis for Catalysis: Used to prepare nitrogen-containing ligands for transition metal catalysts used in cross-coupling and other organic transformations.

Basic Information

Product Name	Thiophen-2-Amine Hydrochloride
CAS No.	18621-53-9
Molecular Formula	C4H6ClNS
Molecular Weight	135.61 g/mol
Synonyms	2-Aminothiophene Hydrochloride; 2-Thiophenamine Hydrochloride; Thiophen-2-ylamine Hydrochloride; 2-Thienylamine Hydrochloride; 2-Thiopheneamine Hydrochloride; α-Aminothiophene Hydrochloride; 2-Amino-thiophene HCl
EINECS	242-438-8

Quality Control

Our Thiophen-2-Amine Hydrochloride is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.