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1-Ethyl-1,4-Dihydro-7-Hydroxy-6-Methoxy-4-Oxoquinoline-3-Carboxylic Acid CAS NO 18465-38-8


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CAS No.:18465-38-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1-Ethyl-1,4-Dihydro-7-Hydroxy-6-Methoxy-4-Oxoquinoline-3-Carboxylic Acid is a high-purity, synthetic organic compound belonging to the quinoline carboxylic acid family, serving as a critical advanced pharmaceutical intermediate. Its value lies in its role as a key building block for the synthesis of complex active pharmaceutical ingredients (APIs), particularly within the fluoroquinolone antibiotic class. This product is essential for research institutions, custom synthesis houses, and pharmaceutical manufacturers engaged in the development and production of novel therapeutic agents.

Application

  • Pharmaceutical Intermediate: Primary use as a core synthon in the multi-step synthesis of fluoroquinolone antibiotics and other quinoline-based therapeutic molecules.
  • API Development: A crucial starting material or intermediate in research and development (R&D) for new antibacterial and antimicrobial agents.
  • Custom Synthesis: Sourced by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.
  • Chemical Research: Used in academic and industrial laboratories to study structure-activity relationships (SAR) and develop new chemical entities.
  • Fine Chemical Production: Integrated into the manufacturing supply chain for high-value, low-volume specialty chemicals.

Basic Information

Product Name 1-Ethyl-1,4-Dihydro-7-Hydroxy-6-Methoxy-4-Oxoquinoline-3-Carboxylic Acid
CAS No. 18465-38-8
Molecular Formula C₁₃H₁₃NO₅
Molecular Weight 263.25 g/mol
Synonyms 7-Hydroxy-6-methoxy-1-ethyl-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; 1-Ethyl-7-hydroxy-6-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; 1-Ethyl-1,4-dihydro-7-hydroxy-6-methoxy-4-oxo-3-quinolinecarboxylic acid; 1-Ethyl-7-hydroxy-6-methoxy-4-oxoquinoline-3-carboxylic acid; 3-Quinolinecarboxylic acid, 1,4-dihydro-1-ethyl-7-hydroxy-6-methoxy-4-oxo-; Intermediate for Fluoroquinolone Antibiotics
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Quality Control

Our 1-Ethyl-1,4-Dihydro-7-Hydroxy-6-Methoxy-4-Oxoquinoline-3-Carboxylic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediate applications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. The container should be kept tightly sealed to protect from moisture.

Specification

Item Specification
Appearance Off-white to light yellow crystalline powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Loss on Drying ≤ 1.0%
Residue on Ignition ≤ 0.2%
Related Substances (HPLC) Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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