Description

Acefylline Piperazine is a high-purity pharmaceutical intermediate and active ingredient. It is valued for its role as a key building block in the synthesis of advanced therapeutic agents, particularly those targeting respiratory and cardiovascular conditions. This compound is essential for manufacturers in the pharmaceutical and fine chemical industries requiring reliable, high-quality raw materials for API production.

Application

• Pharmaceutical Intermediate: Primary use as a critical precursor in the synthesis of bronchodilator and vasodilator active pharmaceutical ingredients (APIs).
• Respiratory Drug Synthesis: Key component in the manufacturing chain for xanthine-derivative medications used to treat asthma, chronic obstructive pulmonary disease (COPD), and other bronchial conditions.
• Cardiovascular Drug Production: Utilized in the development of compounds that improve peripheral blood flow and treat circulatory disorders.
• Fine Chemical Research: Serves as a valuable reagent in organic synthesis and medicinal chemistry research for developing new molecular entities.
• GMP Manufacturing: Supplied for use in cGMP-compliant production processes for regulated markets.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	Acefylline Piperazine
CAS No.	18428-63-2
Molecular Formula	C11H15N5O3
Molecular Weight	265.27 g/mol
Synonyms	Piperazine, 1-(2-hydroxyethyl)-4-(2-((1,2,3,6-tetrahydro-1,3-dimethyl-2,6-dioxo-7H-purin-7-yl)acetyl)-; 7-(2-Hydroxyethyl)theophylline piperazine salt; Acefylline piperazine salt; Etamiphylline; Theophyllineaminoisobutanol; Etophylline; Acetylline piperazine
EINECS	Contact for details

Quality Control

Our Acefylline Piperazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, assay, and impurity profile analysis via HPLC, to ensure it meets stringent pharmaceutical-grade specifications. Certificates of Analysis (COA) documenting full compliance are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. The container must be kept tightly closed to protect the contents from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.