Description

2-Methyl-3-(Trimethylsilyl)Propanoic Acid Methyl Ester is a specialized organosilicon compound that serves as a valuable building block in advanced organic synthesis. Its unique structure, featuring both a silyl-protected carboxylic acid ester and a branched alkyl chain, makes it a versatile reagent for introducing functionalized propanoate units. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of complex molecules, including active pharmaceutical ingredients (APIs) and specialty intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of novel drug candidates, particularly those requiring silyl-protected carboxylic acid derivatives.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where its structural motifs contribute to biological activity.
• Material Science Precursor: Serves as a monomer or modifying agent in the production of specialty silicone-based polymers and coatings.
• Organic Synthesis Reagent: Employed in cross-coupling reactions, nucleophilic substitutions, and as a protected form of a carboxylic acid for complex molecule assembly.
• Flavor & Fragrance Chemistry: Acts as an intermediate for synthesizing esters and other compounds with specific olfactory properties.
• Academic & Industrial R&D: A valuable tool for methodological development and exploring new synthetic pathways in laboratory settings.

Basic Information

Item	Details
Product Name	2-Methyl-3-(Trimethylsilyl)Propanoic Acid Methyl Ester
CAS No.	18388-42-6
Molecular Formula	C8H18O2Si
Molecular Weight	174.31 g/mol
Synonyms	Methyl 2-Methyl-3-(trimethylsilyl)propanoate; Methyl 3-(Trimethylsilyl)-2-methylpropionate; 2-Methyl-3-(trimethylsilyl)propionic acid methyl ester; 3-(Trimethylsilyl)-2-methylpropionic acid methyl ester; Propanoic acid, 2-methyl-3-(trimethylsilyl)-, methyl ester; Methyl 2-methyl-3-trimethylsilylpropanoate; (Trimethylsilyl)methylpropanoate derivative
EINECS	Contact for details

Quality Control

Our production of 2-Methyl-3-(Trimethylsilyl)Propanoic Acid Methyl Ester adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques, including GC and NMR, to confirm identity and quantify purity. A comprehensive Certificate of Analysis (COA) detailing assay, impurity profile, and physical properties is provided with every shipment. We support cGMP-compliant manufacturing for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%
Refractive Index	Contact for details
Density	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.