Description

4,5-Bis(Chloromethyl)-3-Methylthiophene-2-Carboxylic Acid Methyl Ester is a high-value, multi-functional thiophene derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring reactive chloromethyl groups, makes it an essential building block for constructing complex heterocyclic systems and functional materials. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel active ingredients and sophisticated molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) agents and other bioactive heterocycles.
• Agrochemical Synthesis: Building block for developing new generation pesticides, herbicides, and fungicides with enhanced efficacy.
• Material Science Research: Used in the development of organic semiconductors, conductive polymers, and advanced functional materials due to its thiophene core.
• Chemical Synthesis: Versatile reagent for constructing complex fused-ring systems and for introducing functional groups via nucleophilic substitution of the chloromethyl groups.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in catalysis and coordination chemistry.
• Academic & Industrial R&D: Fundamental research compound for exploring new synthetic methodologies and reaction pathways in organic chemistry.

Basic Information

Product Name	4,5-Bis(Chloromethyl)-3-Methylthiophene-2-Carboxylic Acid Methyl Ester
CAS No.	18354-75-1
Molecular Formula	C11H12Cl2O2S
Molecular Weight	279.18 g/mol
Synonyms	Methyl 4,5-Bis(chloromethyl)-3-methyl-2-thiophenecarboxylate; 3-Methyl-4,5-bis(chloromethyl)thiophene-2-carboxylic acid methyl ester; 2-Thiophenecarboxylic acid, 4,5-bis(chloromethyl)-3-methyl-, methyl ester; Methyl 3-methyl-4,5-bis(chloromethyl)thiophene-2-carboxylate
EINECS	Contact for details

Quality Control

Every batch of 4,5-Bis(Chloromethyl)-3-Methylthiophene-2-Carboxylic Acid Methyl Ester is manufactured and tested under strict quality management protocols to ensure consistency and purity for demanding synthetic applications. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in a dark place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.