Description

(Trimethylsilyl)Methylamine is a versatile organosilicon reagent featuring a reactive primary amine group protected by a trimethylsilyl moiety. This compound matters for its dual functionality, serving as a key building block in the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research. Industries that need it include fine chemical manufacturers, pharmaceutical R&D labs, and advanced material scientists who utilize it for introducing amine functionalities under mild conditions.

Application

• Pharmaceutical Intermediates: A key synthon in the production of active pharmaceutical ingredients (APIs), especially for compounds requiring silyl-protected amine groups.
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and insecticides where its silicon-amine chemistry is leveraged.
• Peptide Mimetics & Modifications: Employed in peptide chemistry to introduce silylated amino groups or to create novel peptide backbones.
• Organometallic Catalyst Ligands: Serves as a precursor for ligands in transition metal catalysis, influencing reaction selectivity and yield.
• Surface Modification Agent: Used to functionalize silica, glass, or other oxide surfaces with amine groups for adhesion promotion or further chemical grafting.
• Polymer & Resin Chemistry: Acts as a monomer or cross-linking agent in the synthesis of specialty silicones and silicon-containing polymers.

Basic Information

Product Name	(Trimethylsilyl)Methylamine
CAS No.	18166-02-4
Molecular Formula	C4H13NSi
Molecular Weight	103.24 g/mol
Synonyms	N-[(Trimethylsilyl)methyl]amine; (Trimethylsilylmethyl)amine; Aminomethyltrimethylsilane; N-(Trimethylsilylmethyl)amine; TMSMethylamine; (TMS)CH2NH2; Silanamine, N-(trimethylsilyl)methyl-; 1-Aza-2-silapentane, 2,2,2-trimethyl-
EINECS	242-059-6

Quality Control

Our (Trimethylsilyl)Methylamine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, NMR, and titration, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile and strong alkali/organic solvent nature, store in a cool, well-ventilated place, away from heat and incompatible materials like strong acids and oxidizers. Recommended storage temperature is 2-8°C for long-term stability. Keep container tightly sealed when not in use to prevent moisture absorption and evaporation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.