Description

Trimethylsilylmethanethiol is a versatile organosilicon reagent featuring a reactive thiol group protected by a trimethylsilyl moiety. This compound is valued for its role as a key building block in organic synthesis, particularly for introducing sulfur-containing functional groups under controlled conditions. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for complex molecule construction.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), especially those containing thioether or disulfide linkages.
• Agrochemical Synthesis: Serves as a precursor for creating novel pesticides, herbicides, and fungicides with tailored properties.
• Polymer Modification: Acts as a chain transfer agent or functional monomer in the production of specialty silicones and sulfur-modified polymers.
• Ligand and Catalyst Preparation: Employed in the development of novel ligands for metal-catalyzed reactions and organocatalysts.
• Surface Functionalization: Used to modify material surfaces (e.g., silica, metals) by forming self-assembled monolayers (SAMs) via the thiol group.
• Flavor & Fragrance Industry: A potential intermediate for synthesizing sulfur-containing aroma compounds.

Basic Information

Product Name	Trimethylsilylmethanethiol
CAS No.	18165-76-9
Molecular Formula	C4H12SSi
Molecular Weight	120.29 g/mol
Synonyms	(Trimethylsilyl)methanethiol; (Trimethylsilyl)methyl mercaptan; Trimethylsilylmethyl mercaptan; TMS-CH2-SH; (Mercaptomethyl)trimethylsilane; Silane, (mercaptomethyl)trimethyl-; NSC 163918
EINECS	242-052-9

Quality Control

Our Trimethylsilylmethanethiol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, NMR, and titration methods, to ensure high chemical purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place at room temperature (15-25°C). Due to its highly volatile and light-sensitive nature, containers should be kept tightly sealed and away from heat, sparks, and open flame. Store under an inert atmosphere such as nitrogen for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.