Description

Tetramethylsilane-D12 is a fully deuterated isotopologue of tetramethylsilane, serving as a critical NMR solvent and chemical shift reference standard. Its high isotopic purity and chemical inertness make it essential for obtaining high-resolution, background-free spectra in sensitive nuclear magnetic resonance (NMR) spectroscopy. This compound is indispensable for researchers and quality control laboratories in the pharmaceutical, advanced materials, and academic research sectors, where precise structural elucidation and quantitative analysis are paramount.

Application

• Primary solvent and internal chemical shift reference standard (1H, 13C, 29Si NMR) for high-field NMR spectroscopy.
• Deuterium lock solvent for maintaining magnetic field stability/frequency lock in FT-NMR spectrometers.
• Critical reagent for the analysis of silicon-containing polymers, organometallic compounds, and novel materials.
• Used in the development and validation of NMR methods in pharmaceutical research and development.
• Essential for isotopic labeling studies and mechanistic investigations in chemical reaction pathways.
• Applied in the quality control of deuterated compounds and sensitive chemical intermediates.

Basic Information

Product Name	Tetramethylsilane-D12
CAS No.	18145-38-5
Molecular Formula	C4D12Si
Molecular Weight	100.27 g/mol
Synonyms	Perdeuterated Tetramethylsilane; Tetramethylsilane-d12; TMS-d12; d12-Tetramethylsilane; Deuterated Tetramethylsilane; Tetrakis(trideuteriomethyl)silane; Silicon-29 NMR Reference; NMR Shift Reference Standard
EINECS	Contact for details

Quality Control

Our Tetramethylsilane-D12 is produced and handled under stringent conditions to ensure the highest isotopic and chemical purity required for spectroscopic applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as isotopic purity (D atom %), chemical purity, and NMR suitability. We adhere to rigorous internal quality standards to guarantee batch-to-batch consistency and reliability for your critical research and analytical needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place away from heat and ignition sources. Due to its highly volatile nature, ensure containers are securely sealed and upright to prevent leakage and evaporation. Recommended storage temperature is 2-8°C (refrigerated) to maximize shelf-life stability.

Specification

Item	Specification
Appearance	Colorless clear liquid
Identification (IR)	Conforms
Purity (GC)	≥ 99.5%
Isotopic Purity (D atom %)	≥ 99.5%
Chemical Shift Reference (¹H NMR)	0.00 ppm
Water Content (Karl Fischer)	≤ 0.05%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.