Description

4-Mercaptopyridine-3-Carboxylic Acid is a versatile heterocyclic building block containing both a carboxylic acid and a thiol functional group. This bifunctional nature makes it a critical intermediate for synthesizing complex molecules in pharmaceutical and agrochemical research. It is particularly valuable for medicinal chemists and process development scientists working on active pharmaceutical ingredients (APIs), metal-chelating agents, and advanced materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting neurological disorders and infectious diseases.
• Ligand Synthesis: Used to create chelating ligands for catalysis and metal-organic frameworks (MOFs) due to its thiol and carboxylate binding sites.
• Agrochemical Research: Building block for developing new fungicides and herbicides with specific modes of action.
• Peptide Mimetics: Incorporated into peptide analogs to enhance stability, bioavailability, or introduce specific binding motifs.
• Material Science: Serves as a monomer or cross-linker in the development of functional polymers and surface coatings.
• Chemical Biology Probes: Utilized in the design of activity-based probes and bioconjugation reagents for studying biological processes.

Basic Information

Product Name	4-Mercaptopyridine-3-Carboxylic Acid
CAS No.	18103-73-6
Molecular Formula	C6H5NO2S
Molecular Weight	155.17 g/mol
Synonyms	3-Carboxy-4-mercaptopyridine; 4-Pyridinethiol-3-carboxylic acid; 3-Pyridinecarboxylic acid, 4-mercapto-; 4-Thiol-3-pyridinecarboxylic acid; 4-Sulfanylpyridine-3-carboxylic acid; 4-Mercaptonicotinic acid; 4-Mercapto-3-pyridinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 4-Mercaptopyridine-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to handle under an inert atmosphere for long-term storage and to minimize headspace in opened containers.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.