Description

Ethanone, 2,2,2-Trifluoro-1-(5-Methyl-1H-Pyrrol-2-Yl)- (9Ci) is a specialized trifluoromethyl ketone derivative featuring a pyrrole ring, serving as a high-value synthetic intermediate. This compound matters for its role in introducing the trifluoroacetyl group and heterocyclic motifs, which are critical for modulating the physicochemical and biological properties of target molecules. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, particularly in medicinal chemistry for drug discovery programs.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially those requiring trifluoromethyl ketone pharmacophores for enhanced metabolic stability and binding affinity.
• Agrochemical Research: Used in developing new pesticides and herbicides where the trifluoromethyl group can improve lipophilicity and biological activity.
• Material Science Precursor: Serves as a monomer or functionalization agent in the development of advanced polymers and organic electronic materials.
• Chemical Biology Probe: Utilized in the design of enzyme inhibitors and activity-based probes, leveraging the reactivity of the ketone group.
• Fluorine Chemistry: A valuable substrate for studying novel fluorination reactions and creating fluorine-containing compound libraries.

Basic Information

Product Name	Ethanone, 2,2,2-Trifluoro-1-(5-Methyl-1H-Pyrrol-2-Yl)- (9Ci)
CAS No.	18087-63-3
Molecular Formula	C7H6F3NO
Molecular Weight	177.12 g/mol
Synonyms	1-(5-Methyl-1H-pyrrol-2-yl)-2,2,2-trifluoroethanone; 2,2,2-Trifluoro-1-(5-methyl-1H-pyrrol-2-yl)ethanone; 2,2,2-Trifluoro-1-(5-methylpyrrol-2-yl)ethanone; 2-Acetyl-5-methylpyrrole, 2-trifluoroacetyl; 5-Methyl-2-trifluoroacetylpyrrole; 2-Trifluoroacetyl-5-methylpyrrole; 1-(5-Methyl-2-pyrrolyl)-2,2,2-trifluoroethanone
EINECS	Contact for details

Quality Control

Our Ethanone, 2,2,2-Trifluoro-1-(5-Methyl-1H-Pyrrol-2-Yl)- (9Ci) is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for research and scale-up. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This material is light-sensitive (store away from light) and should be handled under an inert atmosphere for long-term storage to prevent potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.