Description

N-(Trimethylsilylmethyl)Phthalimide is a versatile organosilicon reagent featuring a phthalimide-protected aminomethylsilane group. This compound is valued for its role as a key synthetic intermediate in the preparation of silicon-containing bioactive molecules and advanced materials. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty polymer industries for introducing the trimethylsilylmethylamine moiety into complex structures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of silicon-substituted drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides with modified stability and bioavailability.
• Organosilicon Chemistry: Serves as a protected ammonia equivalent (Gabriel synthesis) for the introduction of aminomethylsilane functional groups.
• Material Science: Intermediate in the production of silicon-based polymers, resins, and surface-modifying agents.
• Cross-Coupling Reactions: Utilized in palladium-catalyzed reactions to create carbon-silicon bonds for further functionalization.
• Ligand and Catalyst Preparation: Building block for synthesizing specialized ligands and organometallic catalysts.

Basic Information

Product Name	N-(Trimethylsilylmethyl)Phthalimide
CAS No.	18042-62-1
Molecular Formula	C₁₂H₁₇NO₂Si
Molecular Weight	235.36 g/mol
Synonyms	1-[(Trimethylsilyl)methyl]-1H-isoindole-1,3(2H)-dione; Phthalimidomethyltrimethylsilane; N-(Trimethylsilylmethyl)phthalimide; Trimethylsilylmethylphthalimide; N-Phthalimidomethyltrimethylsilane; (Phthalimidomethyl)trimethylsilane; TMSM-Phthalimide
EINECS	Contact for details

Quality Control

Our N-(Trimethylsilylmethyl)Phthalimide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high purity and consistency. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	78 - 82 °C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.