Description

2-O,3-O,4-o-Tris(p-Nitrobenzoyl)-β-D-Arabinopyranosyl Bromide is a specialized, high-purity glycosyl bromide derivative used as a critical synthetic intermediate. This compound is valued for its role in constructing complex carbohydrate and nucleoside structures, where precise stereochemistry and functional group protection are paramount. It is essential for researchers and manufacturers in pharmaceutical development, particularly in the synthesis of antiviral and anticancer agents, as well as in advanced carbohydrate chemistry for creating novel glycoconjugates and materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of nucleoside analogs and modified carbohydrates for antiviral and anticancer drug discovery.
• Glycoconjugate Synthesis: Used in the preparation of complex oligosaccharides, glycopeptides, and glycolipids for biological studies and therapeutic applications.
• Chemical Biology Research: Serves as a tool compound for studying glycosylation reactions, enzyme mechanisms, and carbohydrate-protein interactions.
• Material Science: Employed in the development of carbohydrate-based polymers and functionalized surfaces with specific biological recognition properties.
• Process Development: Utilized in scaling up synthetic routes for carbohydrate-active pharmaceutical ingredients (APIs) under controlled GMP-like conditions.

Basic Information

Product Name	2-O,3-O,4-o-Tris(p-Nitrobenzoyl)-β-D-Arabinopyranosyl Bromide
CAS No.	18039-23-1
Molecular Formula	C28H21BrN3O12
Molecular Weight	671.39 g/mol
Synonyms	1-Bromo-2,3,4-tris-O-(4-nitrobenzoyl)-β-D-arabinopyranose; β-D-Arabinopyranosyl Bromide, 2,3,4-Tris-O-(4-nitrobenzoyl)-; 2,3,4-Tri-O-(p-nitrobenzoyl)-α/β-D-arabinopyranosyl Bromide (mixture); Tris(p-nitrobenzoyl) arabinopyranosyl bromide; Arabinopyranosyl bromide tris(4-nitrobenzoate); 18039-23-1; NSC 403796
EINECS	Contact for details

Quality Control

Our 2-O,3-O,4-o-Tris(p-Nitrobenzoyl)-β-D-Arabinopyranosyl Bromide is produced under strict quality management systems. Each batch undergoes comprehensive analytical characterization including HPLC for purity, NMR for structural confirmation, and mass spectrometry to ensure identity and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting research and development under ISO and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening and protected from all light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.