Description

Bicyclo[2.2.2]Octan-2-Ol, 3-Amino-, cis- (8Ci,9Ci) is a specialized, high-purity bicyclic amino alcohol building block. This compound matters for its rigid, three-dimensional structure, which is highly valuable in the design and synthesis of advanced pharmaceutical intermediates and chiral catalysts. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce complex stereochemistry and novel molecular scaffolds into their target molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Asymmetric Catalyst Ligand: Serves as a precursor for sophisticated chiral ligands used in asymmetric hydrogenation and other enantioselective transformations.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where its rigid bicyclic structure confers unique biological activity.
• Material Science Monomer: Employed in the synthesis of specialty polymers and resins with enhanced thermal stability and mechanical properties.
• Academic & Industrial Research: A valuable tool compound for methodological development in organic synthesis and medicinal chemistry programs.
• Fine Chemical Building Block: For the custom synthesis of complex fragrance molecules, dyes, and other high-value specialty chemicals.

Basic Information

Product Name	Bicyclo[2.2.2]Octan-2-Ol, 3-Amino-, cis- (8Ci,9Ci)
CAS No.	17997-65-8
Molecular Formula	C8H15NO
Molecular Weight	141.21 g/mol
Synonyms	cis-3-Aminobicyclo[2.2.2]octan-2-ol; 3-Amino-cis-bicyclo[2.2.2]octan-2-ol; 2-Bicyclo[2.2.2]octanol, 3-amino-, cis-; (1R,2S,4S)-3-Aminobicyclo[2.2.2]octan-2-ol; (1S,2R,4R)-3-Aminobicyclo[2.2.2]octan-2-ol; Bicyclo[2.2.2]octan-2-ol, 3-amino-, (1R,2S,4S)-rel-; Amino BCO derivative
EINECS	Contact for details

Quality Control

Our Bicyclo[2.2.2]Octan-2-Ol, 3-Amino-, cis- (8Ci,9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.