Description

(4-Methoxy-Benzyl)-Trimethyl-Silane is a versatile organosilicon compound featuring a benzyl group substituted with a methoxy moiety and a trimethylsilyl protecting group. This structure makes it a valuable intermediate in organic synthesis, particularly for the protection of alcohols and phenols, and as a building block for more complex molecules. It is essential for research and production in the pharmaceutical, agrochemical, and advanced materials sectors where precise molecular construction is required.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring protected hydroxyl functionalities.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where the silane group acts as a protective or modifying agent.
• Organic Synthesis Reagent: Functions as a versatile reagent for the introduction of the 4-methoxybenzyl (PMB) protecting group for alcohols and phenols in multi-step synthetic routes.
• Material Science Research: Employed in the development of novel silicon-containing polymers, liquid crystals, and other functional materials.
• Flavor & Fragrance Industry: Acts as a precursor in the synthesis of certain aromatic compounds used in perfumery and flavoring agents.
• Cross-Coupling Reactions: Utilized as a substrate in palladium-catalyzed cross-coupling reactions to form new carbon-carbon bonds.

Basic Information

Product Name	(4-Methoxy-Benzyl)-Trimethyl-Silane
CAS No.	17988-20-4
Molecular Formula	C11H18OSi
Molecular Weight	194.35 g/mol
Synonyms	1-(Trimethylsilylmethyl)-4-methoxybenzene; 4-Methoxybenzyltrimethylsilane; p-Methoxybenzyltrimethylsilane; PMB-TMS; Trimethyl(4-methoxybenzyl)silane; (4-Methoxyphenylmethyl)trimethylsilane; Silane, trimethyl[(4-methoxyphenyl)methyl]-; (p-Methoxybenzyl)trimethylsilane
EINECS	Contact for details

Quality Control

Our (4-Methoxy-Benzyl)-Trimethyl-Silane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.