Description

(Azidomethyl)Phosphonic Acid Diethyl Ester is a versatile organophosphorus compound featuring a reactive azide functional group. This unique structure makes it a valuable synthetic intermediate for the preparation of phosphonate derivatives and click chemistry substrates. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries for constructing complex molecules and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those incorporating phosphonate bioisosteres.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators.
• Click Chemistry Reagent: Serves as a phosphonate-containing azide for copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions to create functional polymers and bioconjugates.
• Ligand and Catalyst Development: Precursor for synthesizing specialized phosphonate ligands used in coordination chemistry and catalysis.
• Materials Science Research: Employed in the surface functionalization of materials and the creation of flame-retardant or specialty polymer additives.
• Chemical Biology Probes: Useful for labeling biomolecules or creating activity-based probes for studying enzymatic processes.

Basic Information

Product Name	(Azidomethyl)Phosphonic Acid Diethyl Ester
CAS No.	17982-55-7
Molecular Formula	C5H12N3O3P
Molecular Weight	193.14 g/mol
Synonyms	Diethyl (Azidomethyl)phosphonate; Diethyl Azidomethylphosphonate; (Azidomethyl)phosphonic Acid Diethyl Ester; Azidomethanephosphonic Acid Diethyl Ester; Phosphonic Acid, P-(azidomethyl)-, Diethyl Ester; NSC 169047; Azidomethylphosphonate Diethyl Ester
EINECS	Contact for details

Quality Control

Our (Azidomethyl)Phosphonic Acid Diethyl Ester is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatographic purity assessment and structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing specific results for identity, purity, and impurities is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place at room temperature (15-25°C). This compound is easily oxidized and highly volatile; it is recommended to store under an inert atmosphere such as nitrogen or argon for long-term stability and to minimize decomposition. Keep away from heat, sparks, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.