Description

2-(2-[4-(Trifluoromethyl)Phenyl]-1,3-Thiazol-4-Yl)Acetic Acid is a high-value trifluoromethylated heterocyclic building block, prized for its role in modulating the physicochemical properties of advanced molecules. Its core value lies in enabling the synthesis of novel compounds with enhanced metabolic stability, lipophilicity, and bioavailability. This intermediate is critically needed by pharmaceutical and agrochemical R&D teams for developing new active ingredients, particularly in medicinal chemistry for drug discovery programs.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, especially for kinase inhibitors, anti-inflammatory agents, and CNS-targeted therapies.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides where the trifluoromethyl group improves biological activity and environmental stability.
• Material Science Research: Serves as a precursor for specialty polymers, liquid crystals, and organic electronic materials requiring specific fluorinated motifs.
• Chemical Biology Probes: Employed in the design of molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and fine chemical companies for bespoke synthesis projects and scale-up campaigns.

Basic Information

Product Name	2-(2-[4-(Trifluoromethyl)Phenyl]-1,3-Thiazol-4-Yl)Acetic Acid
CAS No.	17969-63-0
Molecular Formula	C₁₂H₈F₃NO₂S
Molecular Weight	287.26 g/mol
Synonyms	2-[2-[4-(Trifluoromethyl)phenyl]-1,3-thiazol-4-yl]acetic acid; 2-(2-(4-(Trifluoromethyl)phenyl)thiazol-4-yl)acetic acid; 4-Thiazoleacetic acid, 2-[4-(trifluoromethyl)phenyl]-; [2-[4-(Trifluoromethyl)phenyl]-1,3-thiazol-4-yl]acetic acid; 2-(2-(p-Trifluoromethylphenyl)thiazol-4-yl)acetic Acid; 17969-63-0; TFMP-Thiazole Acetic Acid
EINECS	Contact for details

Quality Control

Our production of 2-(2-[4-(Trifluoromethyl)Phenyl]-1,3-Thiazol-4-Yl)Acetic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and LC-MS for impurity profiling. We provide full traceability and detailed Certificates of Analysis (COA) to support your regulatory and R&D requirements, ensuring reliable consistency and supply chain integrity for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep container tightly sealed when not in use to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.