Description

(14α)-3-Methoxy-17-Methylmorphinan-6β-Ol CAS NO 17948-43-5 is a high-purity synthetic organic compound belonging to the morphinan class, a structure of significant pharmaceutical interest. Its precise stereochemistry and functional groups make it a valuable key intermediate and reference standard in advanced research and development. This compound is essential for pharmaceutical companies, contract research organizations (CROs), and academic institutions engaged in the synthesis and study of opioid receptor ligands and central nervous system (CNS) active agents.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of potent analgesic agents and other therapeutic molecules targeting the central nervous system.
• Reference Standard for R&D: Used as a high-purity analytical standard in method development, validation, and quality control for pharmacokinetic and metabolic studies.
• Medicinal Chemistry Research: Provides a core scaffold for structure-activity relationship (SAR) studies to develop new chemical entities with modified pharmacological profiles.
• Analytical Testing: Employed in forensic analysis and regulatory testing as a certified reference material (CRM) for accurate compound identification and quantification.
• Process Development: Used in scaling up synthetic routes and optimizing manufacturing processes for related active pharmaceutical ingredients (APIs).

Basic Information

Product Name	(14α)-3-Methoxy-17-Methylmorphinan-6β-Ol
CAS No.	17948-43-5
Molecular Formula	C₁₉H₂₇NO₂
Molecular Weight	301.43 g/mol
Synonyms	6β-Hydroxy-3-methoxy-17-methylmorphinan; 3-O-Methyl-6β-hydroxymorphinan; 6β-Hydroxy-3-methoxy-N-methylmorphinan; 17-Methyl-3-methoxymorphinan-6β-ol; Morphinan-6β-ol, 3-methoxy-17-methyl-, (14α)-; A key intermediate for opioid analogs
EINECS	Contact for details

Quality Control

Every batch of (14α)-3-Methoxy-17-Methylmorphinan-6β-Ol is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency, meeting the exacting standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data (HPLC, GC, NMR, MS) are available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is light-sensitive and should be stored away from light as indicated.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.