Description

N,n-Dimethyl-4-[(Trimethylsilyl)Oxy]-1H-Indole-3-Ethanamine is a specialized organosilicon derivative of a tryptamine core structure, serving as a key synthetic intermediate in advanced organic chemistry. Its value lies in the strategic protection of the indole hydroxyl group and the functional amine, enabling precise, multi-step synthesis in controlled environments. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active compounds and complex molecular architectures.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel tryptamine-based drug candidates, including potential central nervous system (CNS) agents and serotonin receptor modulators.
• Agrochemical Research: Used in developing new crop protection agents and plant growth regulators that leverage the indole alkaloid scaffold.
• Chemical Synthesis: Serves as a protected precursor in multi-step organic synthesis, where the trimethylsilyl (TMS) group allows for selective reactions at other sites on the molecule.
• Biochemical Research: Employed in the study of enzyme inhibitors and receptor ligands due to its structural similarity to biologically active indoleamines.
• Material Science Exploration: Investigated as a monomer or functional component in the development of specialized polymers and advanced organic materials.

Basic Information

Product Name	N,n-Dimethyl-4-[(Trimethylsilyl)Oxy]-1H-Indole-3-Ethanamine
CAS No.	17943-16-7
Molecular Formula	C15H24N2OSi
Molecular Weight	276.45 g/mol
Synonyms	4-(Trimethylsilyloxy)-N,N-dimethyltryptamine; 4-TMS-O-DMT; 4-Hydroxy-N,N-dimethyltryptamine trimethylsilyl ether; 4-(Trimethylsiloxy)-1H-indole-3-ethanamine, N,N-dimethyl-; 4-OTMS DMT; 17943-16-7; N,N-Dimethyl-4-(trimethylsilyloxy)-1H-indole-3-ethanamine
EINECS	Contact for details

Quality Control

Our N,n-Dimethyl-4-[(Trimethylsilyl)Oxy]-1H-Indole-3-Ethanamine is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.