Description

p-(Trimethylsilyl)Benzenethiol is a specialized organosilicon thiol compound, valued for its unique combination of a reactive thiol (-SH) group and a protective trimethylsilyl moiety. This structure makes it a versatile building block and protective agent in advanced organic synthesis, particularly for the development of pharmaceuticals and functional materials. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require precise sulfur-functionalized intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for constructing sulfur-containing drug candidates and active pharmaceutical ingredients (APIs).
• Ligand Synthesis: Used in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Polymer Modification: Acts as a chain-transfer agent or functional monomer to introduce thiol groups into polymer backbones for cross-linking or surface modification.
• Surface Functionalization: Employed to create self-assembled monolayers (SAMs) on gold and other surfaces for sensor and electronic applications.
• Protecting Group Chemistry: The trimethylsilyl group can protect the thiol functionality during multi-step synthetic sequences.
• Agrochemical Synthesis: Serves as a precursor in the development of novel herbicides, fungicides, and insecticides.

Basic Information

Product Name	p-(Trimethylsilyl)Benzenethiol
CAS No.	17882-12-1
Molecular Formula	C9H14SSi
Molecular Weight	182.36 g/mol
Synonyms	4-(Trimethylsilyl)benzenethiol; (4-Mercaptophenyl)trimethylsilane; p-(Trimethylsilyl)thiophenol; 4-(Trimethylsilyl)thiophenol; Trimethyl(4-sulfanylphenyl)silane; 17882-12-1; p-Trimethylsilylphenyl mercaptan
EINECS	Contact for details

Quality Control

Our p-(Trimethylsilyl)Benzenethiol is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatography (GC/HPLC) and spectroscopic methods (NMR, IR), to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity to oxidation and moisture, containers must be kept sealed and handled under appropriate conditions to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.