Description

3-(Triethylsilyl)-1-Propanethiol CAS NO 17877-45-1 is a specialized organosilicon compound featuring a terminal thiol group protected by a triethylsilyl moiety. This unique structure makes it a valuable intermediate for introducing sulfur-containing functional groups in controlled synthesis environments. It is primarily utilized in advanced material science and pharmaceutical research where precise molecular assembly is critical. Industries requiring high-purity chemical building blocks for custom synthesis will find this reagent essential for their development processes.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs) and complex drug candidates.
• Surface Modification Agent: Used to functionalize silica, glass, and metal oxide surfaces to create self-assembled monolayers (SAMs) with specific chemical properties.
• Polymer Chemistry: Acts as a chain-transfer agent or functional monomer in the synthesis of specialty polymers and silicone-based copolymers.
• Ligand Synthesis: Employed in the preparation of sulfur-containing ligands for catalysis and metal-organic frameworks (MOFs).
• Organic Synthesis: Utilized as a protected thiol reagent in multi-step organic synthesis, particularly in peptide mimetics and natural product synthesis.
• Adhesive & Sealant Formulations: Incorporated as an adhesion promoter and cross-linking agent in high-performance silicone adhesives and sealants.

Basic Information

Product Name	3-(Triethylsilyl)-1-Propanethiol
CAS No.	17877-45-1
Molecular Formula	C9H22SSi
Molecular Weight	190.43 g/mol
Synonyms	3-(Triethylsilyl)propane-1-thiol; 1-Propanethiol, 3-(triethylsilyl)-; Triethylsilylpropanethiol; (3-Mercaptopropyl)triethylsilane; Triethyl(3-mercaptopropyl)silane; TES-Propanethiol; 3-TES-1-Propanethiol; γ-(Triethylsilyl)propyl mercaptan
EINECS	Contact for details

Quality Control

Our 3-(Triethylsilyl)-1-Propanethiol is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Production adheres to current Good Manufacturing Practices (cGMP) where applicable. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We ensure compliance with relevant global regulatory frameworks, including REACH.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Keep away from heat, sparks, and open flame. Due to its sensitivity to oxidation and light, minimize headspace and exposure to air during handling.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.