Description

4-(Trimethylsilyl)Phenylboronic Acid is a versatile organoboron compound featuring both a boronic acid and a trimethylsilyl-protecting group on the phenyl ring. This bifunctional structure makes it a valuable building block in modern synthetic chemistry, particularly for cross-coupling reactions and the construction of complex organic frameworks. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials industries.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds in the synthesis of biaryl compounds, which are common motifs in active pharmaceutical ingredients (APIs) and organic electronic materials.
• Pharmaceutical Intermediate: Serves as a crucial precursor in the development of novel drug candidates, including kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides that require specific aryl-boronic acid intermediates.
• Material Science & OLED Development: Employed in the synthesis of organic semiconductors, liquid crystals, and light-emitting materials for display technologies.
• Polymer Chemistry: Acts as a monomer or chain-transfer agent in the creation of functionalized polymers with tailored properties.
• Protecting Group Strategy: The trimethylsilyl group can be used for temporary protection of reactive sites during multi-step synthetic sequences.

Basic Information

Product Name	4-(Trimethylsilyl)Phenylboronic Acid
CAS No.	17865-11-1
Molecular Formula	C9H15BO2Si
Molecular Weight	194.11 g/mol
Synonyms	(4-Trimethylsilylphenyl)boronic acid; 4-Trimethylsilylbenzeneboronic acid; p-(Trimethylsilyl)phenylboronic acid; B-(4-Trimethylsilylphenyl)boronic acid; 4-TMS-Phenylboronic Acid; 4-Trimethylsilylbenzeneboronic Acid; (4-TMS-Phenyl)boronic Acid; 4-(Trimethylsilyl)benzeneboronic Acid
EINECS	Contact for details

Quality Control

Our 4-(Trimethylsilyl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.