Description

4-Methylumbelliferyl-α-D-Glucopyranoside Hydrate is a high-purity fluorogenic substrate specifically designed for enzymatic assays. This compound is critical for the sensitive and quantitative detection of α-glucosidase activity, a key enzyme in carbohydrate metabolism research. It is an essential reagent for biochemical research, diagnostic kit manufacturing, and pharmaceutical quality control laboratories requiring precise enzyme activity measurements.

Application

• Enzyme Activity Assays: Primary substrate for the fluorometric determination of α-glucosidase activity in research and clinical settings.
• Diagnostic Reagents: Key component in the manufacture of diagnostic kits for metabolic disorders, including Pompe disease and other glycogen storage diseases.
• Biochemical Research: Used in studies of carbohydrate digestion, lysosomal function, and inhibitor screening for diabetes management.
• Pharmaceutical QC: Employed in quality control testing of enzyme replacement therapies and other biopharmaceuticals.
• Microbiology: Applied in microbial identification systems that utilize specific glycosidase activities.
• High-Throughput Screening (HTS): Ideal fluorogenic probe for automated HTS platforms searching for novel enzyme modulators.

Basic Information

Product Name	4-Methylumbelliferyl-α-D-Glucopyranoside Hydrate
CAS No.	17833-43-1
Molecular Formula	C16H18O9 • xH2O
Molecular Weight	354.31 g/mol (anhydrous basis)
Synonyms	4-MU-α-D-Glucopyranoside; 4-Methylumbelliferyl α-D-glucoside; α-Glucosidase Substrate; 4-MU-α-Glc; 4-Methylumbelliferyl-α-D-glucoside Hydrate; 4-MUG; 4-Methylumbelliferyl-α-glucopyranoside; Alfa-glucosidase fluorogenic substrate
EINECS	Contact for details

Quality Control

Every batch of 4-Methylumbelliferyl-α-D-Glucopyranoside Hydrate is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the product meets the high standards required for critical research and diagnostic applications. A detailed Certificate of Analysis (COA), including HPLC purity, identity confirmation (IR, NMR), and specific optical rotation, is supplied with each shipment to guarantee batch-to-batch consistency and performance reliability.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry environment. The product is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Specific Optical Rotation	Contact for details
Water Content (KF)	Contact for details
Fluorogenic Activity	Functional performance tested

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.