Description

Ethyl 2-(6-Bromo-1H-Indol-3-Yl)-2-Oxoacetate is a high-purity, advanced pharmaceutical intermediate characterized by its brominated indole core and α-ketoester functionality. This compound is a critical building block in modern organic synthesis, enabling the construction of complex molecules with high precision and yield. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly in the areas of oncology and neurology.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potent kinase inhibitors and other targeted small-molecule drugs.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products.
• Chemical Biology: Employed as a molecular probe or scaffold in the study of enzyme mechanisms and protein interactions.
• Material Science: Investigated as a monomer or functional component in the creation of specialty polymers and organic electronic materials.
• Academic & Contract Research: Essential for methodological development and discovery chemistry in university and CRO laboratories.

Basic Information

Product Name	Ethyl 2-(6-Bromo-1H-Indol-3-Yl)-2-Oxoacetate
CAS No.	17826-12-9
Molecular Formula	C12H10BrNO3
Molecular Weight	296.12 g/mol
Synonyms	Ethyl 6-Bromo-3-indolylglyoxylate; 2-(6-Bromo-1H-indol-3-yl)-2-oxoacetic acid ethyl ester; Ethyl (6-bromo-1H-indol-3-yl)oxoacetate; 6-Bromoindole-3-glyoxylic acid ethyl ester; 6-Bromo-3-indoleglyoxylic acid ethyl ester; Ethyl α-oxo-(6-bromo-1H-indol-3-yl)acetate; 17826-12-9
EINECS	Contact for details

Quality Control

Our Ethyl 2-(6-Bromo-1H-Indol-3-Yl)-2-Oxoacetate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.