Description

Ethyl 2-(5-Bromo-1H-Indol-3-Yl)-2-Oxoacetate is a high-purity brominated indole derivative, a crucial synthetic intermediate in advanced organic chemistry. This compound is valued for its versatile reactivity, particularly in constructing complex heterocyclic scaffolds and pharmaceutical active ingredients. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for the development of new chemical entities and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators with brominated indole cores.
• Organic Synthesis Reagent: Serves as a versatile precursor for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to create more complex molecular architectures.
• Material Science: Investigated as a monomer or functional additive in the creation of specialized polymers and organic electronic materials.
• Biochemical Research: Employed in the study of enzyme inhibitors and the development of fluorescent probes or molecular tags.

Basic Information

Product Name	Ethyl 2-(5-Bromo-1H-Indol-3-Yl)-2-Oxoacetate
CAS No.	17826-11-8
Molecular Formula	C₁₂H₁₀BrNO₃
Molecular Weight	296.12 g/mol
Synonyms	Ethyl 5-Bromo-3-indolylglyoxylate; Ethyl (5-Bromo-1H-indol-3-yl)-oxoacetate; 5-Bromoindole-3-glyoxylic Acid Ethyl Ester; 2-(5-Bromo-1H-indol-3-yl)-2-oxoacetic Acid Ethyl Ester; 5-Bromo-1H-indole-3-glyoxylic Acid Ethyl Ester; Ethyl α-Oxo-5-bromo-1H-indole-3-acetate; 17826-11-8
EINECS	Contact for details

Quality Control

Our Ethyl 2-(5-Bromo-1H-Indol-3-Yl)-2-Oxoacetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality parameters. Our commitment to quality supports applications in GLP and cGMP environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). Keep away from incompatible materials such as strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.