Description

1-(Chloromethyl)-o-Carborane is a versatile and highly functionalized derivative of the icosahedral carborane cage structure, where a chloromethyl group is attached to one carbon atom. This modification introduces a reactive site for further chemical transformations, making it a critical advanced intermediate in organometallic and materials chemistry. It is essential for researchers and manufacturers in the fields of boron neutron capture therapy (BNCT) agents, high-performance polymers, and thermally stable materials, where the unique properties of the carborane core are leveraged.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing boron-rich compounds used in Boron Neutron Capture Therapy (BNCT) for cancer treatment.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for creating high-temperature resistant polymers, resins, and ceramics with enhanced thermal and chemical stability.
• Organometallic Chemistry: Used to prepare carborane-based ligands for catalysis and to create novel metal-organic frameworks (MOFs) and coordination complexes.
• Advanced Material Synthesis: Intermediate in the production of liquid crystals, dyes, and other specialty materials requiring the unique steric and electronic properties of carboranes.
• Research & Development: A valuable reagent for academic and industrial R&D exploring new applications in medicinal chemistry, nanotechnology, and energy materials.

Basic Information

Product Name	1-(Chloromethyl)-o-Carborane
CAS No.	17786-07-1
Molecular Formula	C3H12B10Cl
Molecular Weight	210.02 g/mol
Synonyms	1-(Chloromethyl)carborane; 1-Chloromethyl-o-carborane; o-Carborane-1-methyl chloride; 1-Chloromethyl-1,2-dicarba-closo-dodecaborane(12); (Chloromethyl)carborane; 1-(Chloromethyl)-1,2-dicarbadodecaborane; 1-(Chloromethyl)-closo-1,2-dicarbadodecaborane
EINECS	Contact for details

Quality Control

Our 1-(Chloromethyl)-o-Carborane is produced under stringent conditions to ensure high purity and batch-to-batch consistency. Each lot undergoes rigorous analytical testing, including NMR, HPLC, and elemental analysis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.