Description

Propylboronic Acid CAS NO 17745-45-8 is a versatile organoboron compound characterized by its propyl chain and reactive boronic acid functional group. This chemical serves as a crucial building block in modern synthetic chemistry, enabling the formation of new carbon-carbon bonds with high selectivity and efficiency. It is primarily utilized by research scientists and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for applications ranging from drug discovery to polymer synthesis.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A fundamental reagent for palladium-catalyzed cross-coupling to create biaryl and alkyl-aryl structures, a cornerstone in pharmaceutical and material science R&D.
• Pharmaceutical Intermediate Synthesis: Used in the construction of complex drug candidates, particularly for introducing the propyl moiety into target molecules during lead optimization.
• Agrochemical Active Ingredient Development: Employed in the synthesis of novel herbicides, fungicides, and insecticides that require specific alkylboron precursors.
• Ligand and Catalyst Preparation: Acts as a precursor for synthesizing specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science and Polymer Chemistry: Incorporated into the synthesis of organic electronic materials, liquid crystals, and functional polymers where boronic acids serve as key linking units.
• Chemical Biology and Proteomics: Utilized in the development of molecular probes and sensors that leverage boronic acid-diol interactions for detection and binding studies.

Basic Information

Product Name	Propylboronic Acid
CAS No.	17745-45-8
Molecular Formula	C3H9BO2
Molecular Weight	87.92 g/mol
Synonyms	n-Propylboronic Acid; 1-Propaneboronic Acid; Propane-1-boronic Acid; Boronic acid, propyl-; Propylborane dihydroxide; B-Propylboronic acid; n-Propylboronic acid (stabilized)
EINECS	Contact for details

Quality Control

Our Propylboronic Acid is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for sensitive cross-coupling reactions. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, water content, and impurity profile.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Due to its sensitivity to oxidation, prolonged exposure to air should be avoided. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.