Description

1,4-Dioxane-D8 is a deuterated analog of 1,4-dioxane, where all eight hydrogen atoms are replaced with deuterium (CAS NO 17647-74-4). This isotopic labeling makes it an essential internal standard and solvent for advanced analytical techniques, particularly Nuclear Magnetic Resonance (NMR) spectroscopy. It is a critical material for researchers and quality control laboratories in the pharmaceutical, agrochemical, and academic sectors who require precise molecular structure elucidation and quantitative analysis.

Application

• Primary use as an NMR solvent and deuterated internal standard for quantitative analysis and structural determination.
• Essential reagent in deuterium labeling studies and reaction mechanism investigations in synthetic organic chemistry.
• Used in the development and validation of analytical methods, including mass spectrometry (MS) and liquid chromatography (LC).
• Critical for pharmaceutical research in drug metabolism and pharmacokinetics (DMPK) studies.
• Employed in material science research for studying polymer dynamics and interactions.
• Application in forensic analysis and environmental testing as a high-purity reference material.

Basic Information

Product Name	1,4-Dioxane-D8
CAS No.	17647-74-4
Molecular Formula	C4D8O2
Molecular Weight	96.15 g/mol
Synonyms	Deuterated 1,4-Dioxane; Dioxane-d8; 1,4-Diethylene Dioxide-d8; [2H8]-1,4-Dioxane; p-Dioxane-d8; Tetrahydro-1,4-dioxin-d8; Ethylene Glycol Ethylene Ether-d8; Perdeuterated 1,4-Dioxane
EINECS	Contact for details

Quality Control

Our 1,4-Dioxane-D8 is produced under stringent conditions to ensure the highest isotopic purity and chemical integrity. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as isotopic enrichment (D atom %), chemical purity, and residual solvent content. We adhere to rigorous quality testing protocols to meet the exacting standards required for spectroscopic and analytical applications. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat and ignition sources. Due to its highly volatile nature, ensure containers are kept upright and securely sealed. Recommended storage temperature is 15-25°C.

Specification

Item	Specification
Appearance	Colorless clear liquid
Identification (IR)	Conforms
Assay (GC)	≥ 99.5%
Deuterium Content (NMR)	≥ 99.5 atom % D
Water Content (KF)	≤ 0.05%
Residual Solvents (GC)	Conforms to ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.