Description

5-Chloroisatin is a versatile and high-value halogenated isatin derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in enabling the efficient construction of complex heterocyclic scaffolds, which are essential for developing novel active compounds. This product is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for applications in drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of kinase inhibitors, antiviral agents, and other bioactive molecules.
• Agrochemical Synthesis: Used in the development of new herbicides and fungicides with novel modes of action.
• Organic Synthesis Reagent: Employed in cyclization and condensation reactions to construct complex indole and quinoline derivatives.
• Material Science Research: Acts as a precursor for functional dyes, pigments, and organic electronic materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme activity and cellular processes.

Basic Information

Product Name	5-Chloroisatin
CAS No.	17630-76-1
Molecular Formula	C8H4ClNO2
Molecular Weight	181.58 g/mol
Synonyms	5-Chloro-1H-indole-2,3-dione; 5-Chloro-2,3-dihydroindole-2,3-dione; 5-Chloroindole-2,3-dione; 5-Chloroisatine; 5-Chlorooxindole; 5-Chloro-2,3-indolinedione; 5-Chloro-1H-indole-2,3(2H,3H)-dione; 5-Chloro-2,3-dioxoindoline
EINECS	Contact for details

Quality Control

Our 5-Chloroisatin is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, identity confirmation via FT-IR and NMR, and residual solvent analysis. A Certificate of Analysis (COA) is supplied with each batch, confirming compliance with agreed specifications. Our quality commitment supports applications requiring stringent material standards, such as pharmaceutical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Melting Point	245 - 250 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.