Description

5,9,10,14B-Tetrahydro-2-Nitroisoquino[2,1-D][1,4]Benzodiazepin-6(7H)-One is a high-purity, specialized heterocyclic organic compound with the CAS number 17617-18-4. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in sophisticated organic synthesis. It is primarily required by pharmaceutical R&D and fine chemical manufacturing sectors for the development of novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel benzodiazepine analogs and other bioactive heterocyclic compounds for medicinal chemistry research.
• Organic Synthesis Building Block: Utilized in complex multi-step syntheses, including cyclization and functionalization reactions, due to its unique fused-ring nitro-substituted structure.
• Research & Development: Essential material for academic and industrial R&D laboratories exploring new chemical entities (NCEs) and structure-activity relationships (SAR).
• Process Chemistry: Used in scale-up and optimization studies for the production of target molecules in pilot plants and commercial manufacturing.
• Reference Standard: Serves as a high-purity analytical standard for method development and quality control in pharmaceutical analysis.

Basic Information

Product Name	5,9,10,14B-Tetrahydro-2-Nitroisoquino[2,1-D][1,4]Benzodiazepin-6(7H)-One
CAS No.	17617-18-4
Molecular Formula	C₁₇H₁₃N₃O₃
Molecular Weight	307.30 g/mol
Synonyms	2-Nitro-5,9,10,14b-tetrahydroisoquino[2,1-d][1,4]benzodiazepin-6(7H)-one; 2-Nitro-5,9,10,14b-tetrahydro-6H-isoquino[2,1-d][1,4]benzodiazepin-6-one; 17617-18-4; Tetrahydro-2-nitroisoquino[2,1-d][1,4]benzodiazepin-6(7H)-one; Isoquino[2,1-d][1,4]benzodiazepin-6(7H)-one, 5,9,10,14b-tetrahydro-2-nitro-
EINECS	Contact for details

Quality Control

Our 5,9,10,14B-Tetrahydro-2-Nitroisoquino[2,1-D][1,4]Benzodiazepin-6(7H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting research-grade specifications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.