Description

4,5,7-Trihydroxycoumarin is a polyphenolic compound belonging to the coumarin class, known for its distinct chemical structure and biological activity. This high-purity intermediate is valued for its role as a key building block in the synthesis of more complex molecules and for its intrinsic functional properties. It is primarily sought by manufacturers and research institutions in the pharmaceutical, nutraceutical, and fine chemical sectors for development and production.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of active pharmaceutical ingredients (APIs) and investigational drugs, particularly those targeting antioxidant and anti-inflammatory pathways.
• Cosmetic & Skincare Actives: Utilized in formulations for its potential antioxidant properties, helping to protect skin from environmental stressors and support product stability.
• Nutraceutical & Dietary Supplements: Incorporated into health supplement formulations where its polyphenolic profile is of interest for wellness applications.
• Biochemical Research: Used as a standard or reagent in life science research to study enzyme inhibition, cellular signaling, and other biological mechanisms.
• Fine Chemical Synthesis: Acts as a versatile scaffold for organic chemists to develop novel compounds with specialized functions for various industrial applications.

Basic Information

Product Name	4,5,7-Trihydroxycoumarin
CAS No.	17575-26-7
Molecular Formula	C9H6O5
Molecular Weight	194.14 g/mol
Synonyms	5,7-Dihydroxy-4-oxo-4H-chromene-2-carboxylic acid; 4,5,7-Trihydroxy-2H-1-benzopyran-2-one; 2H-1-Benzopyran-2-one, 4,5,7-trihydroxy-; 4,5,7-Trihydroxycoumarin; Fraxetin; Fraxetin (coumarin); 7,8-Dihydroxy-6-methoxycoumarin (related isomer); 5,7,8-Trihydroxycoumarin (related isomer)
EINECS	Contact for details

Quality Control

Our 4,5,7-Trihydroxycoumarin is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets exacting standards for research and industrial use. Certificates of Analysis (COA) documenting all critical parameters are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.