Description

1-Phenylethan-2,2,2-D3-Ol CAS NO 17537-32-5 is a deuterium-labeled analog of phenylethanol, a compound of significant interest in advanced chemical synthesis and analytical research. This isotopically labeled version is essential for applications requiring precise molecular tracking, such as in mass spectrometry and NMR spectroscopy, where it serves as a critical internal standard or tracer. It is particularly valuable for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries engaged in metabolic studies, pharmacokinetics, and the development of novel deuterated active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Research & Development: Used as a stable isotope-labeled internal standard in LC-MS and GC-MS for the quantitative analysis of phenylethanol and related compounds in biological matrices.
• Metabolic Pathway Tracing: Serves as a deuterium tracer in studies investigating drug metabolism, degradation pathways, and environmental fate.
• Deuterated API Synthesis: Acts as a key synthetic building block for the preparation of more complex deuterium-labeled molecules, which can exhibit altered metabolic profiles.
• NMR Spectroscopy: Provides a non-radioactive probe for mechanistic studies and structural elucidation due to its distinct spectroscopic signature.
• Fine Chemical Synthesis: Employed in specialized organic synthesis where deuterium incorporation is required to modify chemical or physical properties.
• Quality Control & Reference Standards: Functions as a high-purity certified reference material (CRM) for analytical method development and validation in quality control laboratories.

Basic Information

Product Name	1-Phenylethan-2,2,2-D3-Ol
CAS No.	17537-32-5
Molecular Formula	C8H7D3O
Molecular Weight	125.19 g/mol
Synonyms	Deuterated Phenylethanol; (2,2,2-D3)-1-Phenylethanol; α-Methylbenzyl alcohol-d3; (D3)-1-Phenylethanol; 1-Phenylethanol-2,2,2-d3; (RS)-1-Phenylethanol-d3; (±)-1-Phenylethanol-d3; Styralyl alcohol-d3
EINECS	Contact for details

Quality Control

Our 1-Phenylethan-2,2,2-D3-Ol is produced under strict quality management systems to ensure batch-to-batch consistency and high isotopic purity. Each lot undergoes comprehensive analysis, including assay by GC or HPLC, determination of deuterium enrichment by NMR or MS, and tests for residual solvents and impurities. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support compliance with relevant regulatory frameworks for research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and heat sources. For long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended to maintain stability and isotopic integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR / NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 98.0%
Deuterium Enrichment (NMR/MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.