Description

Ethyl 5-Methyl-4-Oxo-3,4-Dihydrothieno[2,3-D]-Pyrimidine-6-Carboxylate is a high-purity, heterocyclic organic compound that serves as a critical advanced intermediate in modern pharmaceutical synthesis. Its value lies in its complex fused-ring structure, which provides a versatile scaffold for developing novel active pharmaceutical ingredients (APIs). This compound is essential for research chemists and production facilities engaged in the development of new therapeutic agents, particularly within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory pathways.
• Medicinal Chemistry Research: Used extensively in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities with improved efficacy and safety profiles.
• Process Development & Scale-Up: Serves as a critical intermediate for process chemists developing scalable, cost-effective, and robust synthetic routes for potential APIs.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs and CROs engaged in custom synthesis and development services for the global pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for fundamental research in heterocyclic chemistry and the exploration of new bioactive molecules.

Basic Information

Product Name	Ethyl 5-Methyl-4-Oxo-3,4-Dihydrothieno[2,3-D]-Pyrimidine-6-Carboxylate
CAS No.	17417-67-3
Molecular Formula	C10H10N2O3S
Molecular Weight	238.26 g/mol
Synonyms	Ethyl 5-methyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidine-6-carboxylate; 6-Carbethoxy-5-methyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidine; 5-Methyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidine-6-carboxylic acid ethyl ester; Thieno[2,3-d]pyrimidine-6-carboxylic acid, 3,4-dihydro-5-methyl-4-oxo-, ethyl ester; Ethyl 5-methyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidine-6-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 5-Methyl-4-Oxo-3,4-Dihydrothieno[2,3-D]-Pyrimidine-6-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.