Description

Thiourea-D4 is a deuterated isotopologue of thiourea, where four hydrogen atoms are replaced by deuterium. This compound is essential for advanced analytical and research applications where isotopic labeling is required to track molecular pathways or enhance spectroscopic analysis. It is a critical reagent for researchers and manufacturers in the pharmaceutical, agrochemical, and analytical chemistry sectors who require high-purity, isotopically labeled materials for mass spectrometry, NMR spectroscopy, and metabolic studies.

Application

• Internal Standard for Mass Spectrometry (MS): Used as a quantitative reference standard in LC-MS and GC-MS analysis to ensure accuracy in pharmaceutical and bioanalytical testing.
• NMR Spectroscopy Solvent & Reagent: Serves as a deuterated solvent shift reagent or a labeled precursor in nuclear magnetic resonance studies to elucidate molecular structure and dynamics.
• Metabolic Pathway Tracing: Employed in pharmacokinetics and drug metabolism research to trace the biological fate of thiourea-containing compounds using stable isotope labeling techniques.
• Chemical Synthesis Intermediate: Acts as a labeled building block for the synthesis of deuterated pharmaceuticals, agrochemicals, and specialty organic compounds.
• Analytical Reference Material: Provides a certified reference material for calibrating instruments and validating analytical methods in quality control laboratories.
• Research in Reaction Mechanisms: Utilized in mechanistic studies to investigate reaction kinetics and isotopic effects in chemical and biochemical processes.

Basic Information

Product Name	Thiourea-D4
CAS No.	17370-85-3
Molecular Formula	CD4N2S
Molecular Weight	80.16 g/mol
Synonyms	Deuterated Thiourea; Thiourea-d4; [2H4]-Thiourea; Thiocarbamide-d4; Isotopic Thiourea; Sulfourea-d4; Deuterium Labeled Thiourea; NSC 5031-d4
EINECS	Contact for details

Quality Control

Our Thiourea-D4 is manufactured under strict quality systems to ensure high isotopic and chemical purity suitable for sensitive analytical applications. Each batch is characterized by advanced spectroscopic methods, including NMR and MS, to confirm deuterium incorporation and chemical identity. A comprehensive Certificate of Analysis (COA) detailing isotopic purity, chemical assay, and impurity profile is provided with every shipment to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Deuterium Content (NMR)	≥ 98 atom % D
Assay (HPLC)	≥ 98.0%
Chemical Purity	≥ 99.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.