Description

3-Chlorothiophene is a versatile halogenated heterocyclic compound that serves as a critical building block in advanced organic synthesis. Its value lies in its reactivity, which enables the efficient construction of complex molecules for high-performance materials and active pharmaceutical ingredients. This intermediate is essential for R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new compounds with tailored properties.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in antiviral and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the manufacture of advanced pesticides and herbicides, where the thiophene ring contributes to biological activity.
• Material Science: Serves as a monomer or precursor in the synthesis of conductive polymers, organic semiconductors, and liquid crystals for electronic applications.
• Organic Synthesis: A valuable reagent for cross-coupling reactions (e.g., Suzuki, Stille) and functional group transformations in complex molecule assembly.
• Dye & Pigment Manufacturing: Employed as an intermediate in the production of specialized dyes and pigments for industrial applications.

Basic Information

Product Name	3-Chlorothiophene
CAS No.	17249-80-8
Molecular Formula	C4H3ClS
Molecular Weight	118.58 g/mol
Synonyms	3-Chlorothiophene; Thiophene, 3-chloro-; 3-Chlorothiofuran; 3-CT; β-Chlorothiophene; 3-Chloro-1-thia-2,4-cyclopentadiene; NSC 404099
EINECS	241-300-9

Quality Control

Our 3-Chlorothiophene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use. Recommended storage temperature: 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Total impurities ≤ 2.0%
Density (at 20°C)	1.30 - 1.35 g/mL
Refractive Index (n20D)	1.550 - 1.560

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.