Description

Benzoic Acid-18O2 is a stable isotope-labeled analog of benzoic acid, where two oxygen atoms are replaced by the oxygen-18 isotope. This compound is essential for advanced analytical research, serving as a critical internal standard and tracer in mass spectrometry and metabolic studies. It is primarily utilized by research institutions, pharmaceutical developers, and analytical laboratories engaged in pharmacokinetics, proteomics, and environmental fate analysis.

Application

• Internal standard for the precise quantification of benzoic acid and related compounds in complex matrices via Gas Chromatography-Mass Spectrometry (GC-MS) and Liquid Chromatography-Mass Spectrometry (LC-MS).
• Tracer compound in metabolic pathway studies and drug metabolism research (DMPK) to elucidate biotransformation processes.
• Critical reagent in the development and validation of high-sensitivity analytical methods for food safety and environmental monitoring.
• Used in proteomics and biomarker discovery research as a tool for accurate mass calibration and signal referencing.
• Starting material or reference standard in the synthesis of other isotope-labeled pharmaceutical intermediates and fine chemicals.
• Applied in scientific research investigating chemical reaction mechanisms where oxygen atom transfer is studied.

Basic Information

Product Name	Benzoic Acid-18O2
CAS No.	17217-84-4
Molecular Formula	C7H618O2
Molecular Weight	124.09 (for 18O2 labeled form)
Synonyms	Benzoic-18O2 Acid; Benzene-18O2-carboxylic Acid; 18O2-Benzoic Acid; Benzoic Acid (O-18O2); Benzoic Acid, Labeled with Oxygen-18; Carboxy-18O2-benzene; Phenyl-18O2-formic Acid; Dracylic-18O2 Acid
EINECS	Contact for details

Quality Control

Our Benzoic Acid-18O2 is manufactured under strict quality protocols to ensure high isotopic and chemical purity, essential for reliable research data. Each batch is analyzed using advanced techniques including NMR and Isotope Ratio Mass Spectrometry (IRMS). A comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (atom % 18O), chemical purity, and identity confirmation is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be stored away from direct light exposure to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Isotopic Enrichment (Atom % 18O)	≥ 95%
Chemical Purity (HPLC)	≥ 98.0%
Melting Point	121 - 123 °C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.