Description

Diethyl 2,2-Dimethoxyethylphosphonate is a high-purity organophosphorus compound, serving as a versatile and critical reagent in advanced organic synthesis. Its primary value lies in its role as a key building block for the preparation of complex molecules, particularly in pharmaceutical and agrochemical research. This product is essential for chemists and manufacturers in the fine chemical, pharmaceutical intermediate, and specialty materials sectors who require reliable, high-quality synthetic precursors.

Application

• Pharmaceutical Intermediate Synthesis: A crucial reagent in the Horner-Wadsworth-Emmons (HWE) olefination reaction for constructing carbon-carbon double bonds in active pharmaceutical ingredients (APIs).
• Agrochemical Manufacturing: Used in the synthesis of complex phosphonate-based herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Acts as a key precursor for synthesizing specialty chemicals, including flame retardants, plasticizers, and complex ligands for catalysis.
• Material Science Research: Employed in the development of novel polymers and functional materials where phosphonate groups are required for specific properties.
• Academic & R&D Laboratories: A standard reagent for methodological development in organic synthesis and for creating libraries of novel compounds for screening.

Basic Information

Product Name	Diethyl 2,2-Dimethoxyethylphosphonate
CAS No.	17053-13-3
Molecular Formula	C8H19O5P
Molecular Weight	226.21 g/mol
Synonyms	Diethyl (2,2-dimethoxyethyl)phosphonate; (2,2-Dimethoxyethyl)phosphonic Acid Diethyl Ester; Diethyl (2,2-dimethoxyethyl)phosphonate; 2,2-Dimethoxyethylphosphonic Acid Diethyl Ester; Diethyl 2,2-Dimethoxyethylphosphonate; Phosphonic acid, (2,2-dimethoxyethyl)-, diethyl ester; Diethyl (dimethoxymethyl)methylphosphonate (related isomer)
EINECS	241-143-8

Quality Control

Our Diethyl 2,2-Dimethoxyethylphosphonate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.430 - 1.435
Density (20°C)	1.10 - 1.15 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.